Charles Polsky, M.D., is a biotechnology entrepreneur with over twenty years of experience working with startups in the life sciences. He has served in several executive positions, including co-founder of the molecular diagnostic 3PrimeDx (2016-19) developing a cardiac arrhythmia biomarker to predict sudden cardiac death risk; CEO of the gene-delivery company SonoGene (2019-20), which developed ultrasound-induced sonoporation to facilitate focused payload delivery of genetic material; board member of Impossible Objects (2016-present), which is developing an additive manufacturing platform; Executive Board Chair of Bolden Therapeutics, which is developing drugs to enhance endogenous neurogenesis as a means to treat degenerative diseases of the CNS; and Executive Advisor to ReAx Biotherapeutics, which is developing its proprietary SPARC drug discovery engine to hit traditionally-undruggable targets within the Oncology space and beyond, among others. From 2015-2019, Dr. Polsky served as President and CEO of William Harris Investors, a Chicago-based family investment office, and oversaw day-to-day operations of a 35-person staff managing investing, asset allocation, tax accounting and estate planning, trust administration and other services. Beginning in 2019, he retired as CEO of William Harris Investors to pursue early-stage biotechnology consulting fulltime. Since then, engagements have included CEO at SonoGene (Gene Delivery Startup, 2019-2020), Executive Board Chair at RigImmune (Yale University Oncology startup; 2020-21), Executive Board Chair at Bolden Therapeutics (2020-present), Executive Advisor to ReAx Bio (UChicago Cancer drug discovery startup; 2021-present), and Executive Board Chair for Beyond Barriers Therapeutics (2022-present), a developer of intranasal N-acetyl cysteine to treat traumatic brain injury (2022-present). In his various board and advisory capacities, Dr. Polsky has provided strategic guidance, negotiated licenses and material transfer agreements (MTAs) with universities, created pro forma budgets, participated in discussions pertaining to scientific, regulatory, drug development and other technical topics, set up PEO benefits packages for employees and helped create employee handbooks and other corporate governance materials.Beyond his work above, Dr. Polsky has been a named author on several peer-reviewed academic scientific publications and was elected to the Alpha Omega Alpha Medical Honor Society in 1997. He holds an M.D. from the University of Chicago and a BA in Mathematics from Yale University, and presently lives in Chicago with his wife and youngest daughter.